The Nielsen Rating's Top 20 TV Shows for April 19 - April 25. The first number is the ranking, the second number is the season average, then the show name and network. The last number represents the number of viewers in millions. An asterisk * indicates a tie.| Rank | Season avg. rank | Show name | Network | Viewers in millions | Season-to-date average (in millions) |
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| 1. | 3 | Dancing With the Stars | ABC | 21.1 | 19.6 |
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| 2. | 1 | American Idol (Tues.) | Fox | 19.7 | 25.6 |
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| 3. | 2 | American Idol (Wed.) | Fox | 18.8 | 23.9 |
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| 4. | 7 | The Mentalist | CBS | 15.0 | 16.8 |
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| 5. | 10 | Dancing With the Stars Results | ABC | 13.6 | 15.5 |
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| 6. | 8 | CSI | CBS | 13.4 | 15.8 |
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| 7. | 49 | Glee | Fox | 13.0 | 8.6 |
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| 8. | 17 | Survivor: Heroes | CBS | 11.9 | 13.4 |
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| 9. | 21 | CSI: Miami | CBS | 11.7 | 12.8 |
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| * | 14 | The Big Bang Theory | CBS | 11.7 | 14.2 |
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| 11. | 17 | 60 Minutes | CBS | 11.4 | 13.5 |
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| * | 12 | Two and a Half Men | CBS | 11.4 | 14.8 |
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| 13. | 15 | Desperate Housewives | ABC | 11.3 | 14.0 |
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| 14. | 23 | House | Fox | 10.8 | 12.6 |
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| 15. | 32 | Romantically Challenged | ABC | 10.7 | 10.7 |
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| 16. | 27 | Amazing Race | CBS | 10.6 | 11.1 |
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| 17. | 33 | Castle | ABC | 10.4 | 10.4 |
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| 18. | 8 | NCIS: Los Angeles (rpeat) | CBS | 10.3 | 15.7 |
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| 19. | 5 | NCIS (repeat) | CBS | 10.0 | 18.9 |
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| 20. | 27 | Lost | ABC | 9.5 | 11.9 |
